Blar i forfatter "Raymond, Warren David"

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    • Association of Achieving Lupus Low Disease Activity State Fifty Percent of the Time With Both Reduced Damage Accrual and Mortality in Patients With Systemic Lupus Erythematosus 

      Sharma, Chanakya; Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-01)
      <i>Objective</i> - To assess the impact of achieving Lupus Low Disease Activity State ≥50% of the time (LLDAS‐50) on damage accrual and mortality in an inception cohort of patients with systemic lupus erythematosus (SLE).<p><p> <i>Methods</i> - We used data from the Tromsø Lupus Cohort, a longitudinal population‐based study of all patients with SLE in the 2 northernmost counties in Norway. ...

    • Hypocomplementemia as a Risk Factor for Organ Damage Accrual in Patients with Systemic Lupus Erythematosus 

      Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-30)
      While it is a common practice to monitor complement levels in patients with systemic lupus erythematosus to aid in flare prediction and detection, it is unclear if this strategy is helpful in preventing subsequent organ damage. We studied longitudinal complement levels in 102 SLE patients during a median follow-up of 13.8 years (IQR 7.0, 23.1). Low complement was defined as C3 < 0.84 g/L and/or ...

    • The Impact of Cytokines on the Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus 

      Raymond, Warren David; Eilertsen, Gro Østli; Shanmugakumar, Sharanyaa; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-15)
      <i>Introduction</i>: Systemic lupus erythematosus (SLE) reduces the health-related quality of life (HRQoL), even during periods of disease quiescence. We investigated whether subclinical inflammation as reflected by cytokine levels is linked with reduced HRQoL. Methods: A cross-sectional study of SLE patients (<i>n</i> = 52, mean age 47.3, 86.5% female) who completed a Short Form Health Survey-36 ...

    • Smoking associates with increased BAFF and decreased interferon-γlevels in patients with systemic lupus erythematosus 

      Raymond, Warren David; Hamdorf, Matthew; Furfaro, Michael; Eilertsen, Gro Ostli; Nossent, Johannes Cornelis (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-01)
      Objective - In SLE, smoking increases the burden of cutaneous disease and organ damage, and leads to premature mortality. However, the effect of smoking on disease manifestations and cytokine levels of patients with SLE is unclear. This study compared characteristics of patients with SLE across smoking status, and determined the association of smoking with serum cytokine levels.<p> <p>Method - A ...

    • Soluble erythropoietin receptor levels associate with inflammatory mediators but not with disease activity or cumulative organ damage in patients with systemic lupus erythematosus 

      Jones, Heather; Raymond, Warren David; Eilertsen, Gro Østli; Nossent, Johannes (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-14)
      The erythropoietin receptor (EpoR) stimulates erythrocyte proliferation after erythropoietin binding. EpoR belongs to the cytokine receptor superfamily and can be found on macrophages and endothelial cells. As there are no data on the role of EpoR systemic autoimmune diseases, we investigated the role of soluble EpoR (sEpoR) in patients with systemic lupus erythematosus (SLE). In a cross-sectional ...